HCC38（人乳腺原发性导管癌）
CBP60417
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| I. General information | |
| Synonyms: | HCC38 |
| Background: | HCC38 was initiated from a 50-year-old white female with a prior history of leiomyosarcoma; her mother died of breast cancer. This cell line was initiated on 4/27/92 and took 32 months to establish. |
| Species: | Homo sapiens, human |
| Tissue: | mammary gland; breast/duct |
| Disease: | TNM stage IIB, grade 3, primary ductal carcinoma |
| Gender: | female, 50 years adult, Caucasian, White |
| Morphology: | epithelial |
| Growth Mode: | adherent, single cells and loosely attached clusters |
| Doubling Time: | N/A |
| DNA Profile: | Amelogenin: X CSF1PO: 12 D13S317: 12,14 D16S539: 10,14 D5S818: 9 D7S820: 10 THO1: 9.3 TPOX: 9,12 vWA: 16,17 Cobioer’s Cell Line Authentication Service |
| Culture Medium: |
RPMI-1640+10%FBS HCC38完全培养基，# CBP60417M |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Antigen Expression: | N/A |
| Receptor Expression: | estrogen receptor, not expressed progesterone receptor, not expressed |
| Oncogene: | her2/neu -; p53 + |
| Genes Expressed: | Epithelial glycoprotein 2 [EGP2]; cytokeratin 19 |
| Cellular Products: | Epithelial glycoprotein 2 [EGP2]; cytokeratin 19 |
| Tumor Formation: | N/A |
| Comments: | HCC38 is positive for the epithelial cell specific marker Epithelial Glycoprotein 2 [EGP2] and for cytokeratin 19, and is negative for expression of estrogen receptor (ER) and progesterone receptor (PR). The cells are negative for expression of Her2-neu but positive for expression of p53 The tumor was classified as TMN Stage IIB, Grade 3, with 3/28 lymph node metastasis. For more information, please contact Cobioer (4008-750-250). |
