HCC1599（人乳腺原发性导管癌）
CBP60415
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| I. General information | |
| Synonyms: | HCC1599 |
| Background: | The HCC1599 breast cancer cell line was initiated on March 28, 1995, and took 10 months to establish. |
| Species: | Homo sapiens, human |
| Tissue: | mammary gland; breast/duct |
| Disease: | TNM stage IIIA, grade 3, primary ductal carcinoma |
| Gender: | female, 44 years adult, Caucasian, White |
| Morphology: | epithelial |
| Growth Mode: | suspension, multicell aggregates |
| Doubling Time: | N/A |
| DNA Profile: | Amelogenin: X CSF1PO: 12 D13S317: 11 D16S539: 12,13 D5S818: 12 D7S820: 10,11 THO1: 9.3 TPOX: 8 vWA: 17 Cobioer’s Cell Line Authentication Service |
| Culture Medium: |
RPMI1640+20%FBS HCC1599完全培养基，# CBP60415M |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Antigen Expression: | N/A |
| Receptor Expression: | estrogen receptor, negative progesterone receptor, negative |
| Oncogene: | her2/neu -, p53 - |
| Genes Expressed: | Epithelial glycoprotein 2 [EGP2]; cytokeratin 19 |
| Cellular Products: | Epithelial glycoprotein 2 [EGP2]; cytokeratin 19 |
| Tumor Formation: | N/A |
| Comments: | The tumor was classified as a TNM stage IIIA, grade 3, invasive ductal carcinoma. Information regarding lymph node metastasis is not available. The cells are poorly differentiated. The cells are negative for expression of Her2-neu and for expression of p53. The cells are negative for expression of estrogen receptor (ER) and for expression of progesterone receptor (PR). HCC1599 is positive for the epithelial cell specific marker Epithelial Glycoprotein 2 (EGP2), and for cytokeratin 19. An EBV-transformed lymphoblastoid cell line (HCC1599 BL) from the same patient is available as ATCC CRL-2332. For more information, please contact Cobioer (4008-750-250). |
