Toledo（人弥漫性大细胞淋巴瘤）
CBP61167
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| I. General information | |
| Synonyms: | Toledo |
| Background: | Toledo was established in 1990 from peripheral blood leukocytes (PBL) of a patient that originally had a diffuse large cell lymphoma (DLCL). |
| Species: | Homo sapiens, human |
| Tissue: | peripheral blood |
| Disease: | diffuse large cell lymphoma; non-Hodgkin's B cell lymphoma |
| Gender: | female, adult, White |
| Morphology: | lymphoblast |
| Growth Mode: | suspension |
| Doubling Time: | 24 to 30 hrs |
| DNA Profile: | D5S818:10,12 D7S820: 9,10 THO1: 8,9.3 TPOX: 8,11 vWA: 16,17 Amelogenin: X CSF1PO: 12 D13S317:11 D16S539:9 Cobioer’s Cell Line Authentication Service |
| Culture Medium: |
RPMI-1640+20%FBS Toledo完全培养基，# CBP61167M |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Antigen Expression: | CD10 +, CD19 +, CD20 +, CD38 +, CD23 -, CD39 - Ref |
| Receptor Expression: | N/A |
| Karyotype | N/A |
| Virus Susceptibility | N/A |
| Oncogene: | N/A |
| Genes Expressed: | N/A |
| Cellular Products: | N/A |
| Tumor Formation: | N/A |
| Comments: | Following high-dose chemotherapy and bone marrow transplantation, the patient subsequently developed a lymphoma in the brain. Though the morphology of the cells resembles Burkitt's lymphoma, the cells lack the typical chromosomal translocations of Burkitt's lymphoma. The karyotype does exhibit multiple chromosomal aberrations. The cells do not express surface or cytoplasmic immunoglobulin. The cells are negative for Epstein-Barr virus. For more information, please contact Cobioer (4008-750-250). |
