SUP-B15（人急性淋巴细胞白血病）
CBP61164
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| I. General information | |
| Synonyms: | SUP-B15 |
| Background: | This line was was derived from malignant cells collected from the bone marrow of an 8 year old child with Philadelphia chromosome positive B cell ALL. |
| Species: | Homo sapiens, human |
| Tissue: | bone marrow |
| Disease: | acute lymphoblastic leukemia |
| Gender: | male, 8 years, Caucasian |
| Morphology: | lymphoblast |
| Growth Mode: | suspension |
| Doubling Time: | 18 hrs |
| DNA Profile: | Amelogenin: X,Y CSF1PO: 11,12 D13S317: 8,14 D16S539: 11,12 D5S818: 12,13 D7S820: 10,11 THO1: 6,9.3 TPOX: 8,9 vWA: 15,17 Cobioer’s Cell Line Authentication Service |
| Culture Medium: |
IMDM+0.05 mM 2-mercaptoethanol+20%FBS SUP-B15完全培养基，# CBP61164M |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Antigen Expression: | CD1a -; CD2 -; CD3 -; CD4 -; CD5 -; CD8 -; CD10 +; CD13 +; CD38 +; CD71 +; HLA DR + |
| Receptor Expression: | N/A |
| Karyotype | N/A |
| Virus Susceptibility | N/A |
| Oncogene: | N/A |
| Genes Expressed: | immunoglobulin (cytoplasmic) |
| Cellular Products: | immunoglobulin (cytoplasmic) |
| Tumor Formation: | N/A |
| Comments: | The cells express multiple B lineage markers, but do not express T cell markers. The cells are positive for the beta-2-microglobulin, Leu12, My7 (CD13), OKT9 (CD71), OKT10 (CD38) and CALLA (CD10) antigens. They are are negative for CB1, Leu 1 (CD5), Leu2 (CD8), Leu3 (CD4), Leu4 (CD3), Leu5 (CD2), Leu6 (CD1a), Leu9, Leu M1 (CD15), My9 (CD33), surface immunoglobulin (sIg -) and Epstein-Barr virus. For more information, please contact Cobioer (4008-750-250). |
