ZR-75-1（人乳腺癌细胞）
CBP60402
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| I. General information | |
| Synonyms: | ZR-75-1 |
| Background: | Derived from a malignant ascitic effusion in a 63 year old female Caucasian with infiltrating ductal carcinoma. The cells are reported to express both the wildtype and variant oestrogen receptors, progesterone receptor and other steroid hormones. |
| Species: | Homo sapiens, human |
| Tissue: | mammary gland; breast/duct; derived from metastatic site: ascites |
| Disease: | ductal carcinoma |
| Gender: | female, 63 years adult, Caucasian |
| Morphology: | epithelial |
| Growth Mode: | adherent |
| Doubling Time: | 80 hrs |
| DNA Profile: | Amelogenin: X CSF1PO: 10,11 D13S317: 9 D16S539: 11 D5S818: 13 D7S820: 10,11 THO1: 7,9.3 TPOX: 8 vWA: 16,18 Cobioer’s Cell Line Authentication Service |
| Isoenzymes | G6PD, B |
| Culture Medium: |
RPMI-1640+10%FBS+1% ITS-G (GIBCO 41400045) ZR-75-1完全培养基，# CBP60402M |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Antigen Expression: | N/A |
| Receptor Expression: | estrogen receptor, expressed |
| Oncogene: | N/A |
| Genes Expressed: | mucin (apomucin, MUC-1, MUC-2) |
| Cellular Products: | mucin (apomucin, MUC-1, MUC-2) |
| Tumor Formation: | Yes, forms tumors in nude mice |
| Comments: | The cells produce high levels of MUC-1 mucin mRNA, low levels of MUC-2 mRNA but do not express the MUC-3 gene. For more information, please contact Cobioer (4008-750-250). |
