HCC1419（人乳腺癌细胞）
CBP60371
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| I. General information | |
| Synonyms: | HCC1419 |
| Background: | This cell line was initiated on 12/28/94 from a patient who received prior chemotherapy with no previous family history of breast cancer. The line took 9 months to establish. |
| Species: | Homo sapiens, human |
| Tissue: | mammary gland; breast |
| Disease: | TNM stage IIIA, grade 3,primary ductal carcinoma |
| Gender: | female, 42 years, Hispanic |
| Morphology: | epithelial |
| Growth Mode: | adherent |
| DNA Profile: | Amelogenin: X CSF1PO: 10,12 D13S317: 9,12 D16S539: 11,12 D5S818: 10,12 D7S820: 11 THO1: 6,9.3 TPOX: 8 vWA: 16,17 Cobioer’s Cell Line Authentication Service |
| Culture Medium: |
RPMI-1640+10%FBS HCC1419完全培养基，# CBP60371M |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Receptor Expression: | estrogen receptor, negative progesterone receptor, negative |
| Oncogene: | her2/neu +, p53 - |
| Genes Expressed: | Epithelial glycoprotein 2 [EGP2]; cytokeratin 19 |
| Cellular Products: | Epithelial glycoprotein 2 [EGP2]; cytokeratin 19 |
| Comments: | The tumor was classified as TNM stage IIIA, grade 3, invasive ductal carcinoma with 5 out of 5 lymph node metastasis. The cells are poorly differentiated. The cells overexpress Her2-neu but are negative for expression of p53. HCC1419 is positive for the epithelial cell specific marker epithelial glycoprotein 2 (EGP2) and for cytokeratin 19. The cells are negative for expression of estrogen receptor (ER) and for expression of progesterone receptor (PR). For more information, please contact Cobioer (4008-750-250). |
