HLA-E aAPC Cell
CBP74242
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| I. Background | |
| HLA-E (Major Histocompatibility Complex, Class I, E) is a Protein Coding gene. Diseases associated with HLA-E include Choriocarcinoma and Senile Entropion. | |
| II. Background | |
| HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. Figure 1. HLA-E aAPC Cell 细胞模型原理图 |
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| III. Introduction | |
| Expressed gene: | NKG2A |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | F12K +10%FBS+ 3 μg/ml puromycin + 600 μg/ml Hygromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Functional(Report Gene) Assay |
| IV. Representative Data | |
Figure 2. Dose Response of NKG2A Blocking Ab in NKG2A Effector Reporter Cell(C56) With HLA-E aAPC Cell.
