U-118MG（人脑星形胶质母细胞瘤）
CBP60305
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| I. General information | |
| Synonyms: | U-118MG |
| Background: | U-118 MG and U-138 MG are very similar cytogenetically and share at least six derivative marker chromosomes. This is one of a number of cell lines derived from malignant gliomas (see also ATCC HTB-14 and ATCC HTB-16) by J. Ponten and associates from 1966 to 1969. |
| Species: | Homo sapiens, human |
| Tissue: | brain |
| Disease: | classified as grade IV as of 2007, glioblastoma; astrocytoma |
| Gender: | male, 50 years, Caucasian |
| Morphology: | epithelial |
| Growth Mode: | adherent |
| DNA Profile: | Amelogenin: X,Y CSF1PO: 11,12 D13S317: 9 D16S539: 12,13 D5S818: 11 D7S820: 9 THO1: 6 TPOX: 8 vWA: 18 Cobioer’s Cell Line Authentication Service |
| Culture Medium: |
DMEM+10%FBS U-118MG完全培养基，# CBP60305M |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Antigen Expression: | Blood Type A, Rh+; HLA Aw24, A28, B12, Bw47 |
| Tumor Formation: | Yes, in nude mice inoculated subcutaneously with 10(7) cells (Tumors developed within 21 days at 100% frequency (5/5).) |
| Comments: | NOTE: The two glioblastoma cell lines, U-118 MG (HTB-15) and U-138 MG (HTB-16), reportedly from different individuals have identical VNTR and similar STR patterns. U-118 MG and U-138 MG are very similar cytogenetically and share at least six derivative marker chromosomes. Mycoplasma contamination was eliminated in 1987 by treatment with BM-Cycline over a six week culture period. For more information, please contact Cobioer (4008-750-250). |
