MSTO-211H（人双向性肺癌细胞）
CBP60109
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| I. General information | |
| Synonyms: | MSTO-211H |
| Background: | The MSTO-211H cell line was established in 1985 from the pleural effusion of a patient with biphasic mesothelioma of the lung.,Derived from metastatic site, lung |
| Species: | Homo sapiens, human |
| Tissue: | lung; derived from metastatic site: pleural effusion |
| Disease: | biphasic mesothelioma |
| Gender: | male,62 years, Caucasian |
| Morphology: | fibroblast |
| Growth Mode: | adherent |
| Doubling Time: | 20 hrs |
| DNA Profile: | Amelogenin: X,Y CSF1PO: 11,12 D13S317: 11,14 D16S539: 13 D5S818: 12 D7S820: 8,12 THO1: 8,9.3 TPOX: 11 vWA: 16,18 Cobioer’s Cell Line Authentication Service |
| Culture Medium: |
RPMI-1640+10%FBS MSTO-211H完全培养基，#CBP60109M |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Oncogene: | c-myc +; v-src +; v-abl +; v-erb B +; c-raf 1 +; H-ras +; K-ras +; N-ras +; N-myc -; L-myc -; c-myb -; c-fos -; v-fes -; v-fms -; v-sis - |
| Tumor Formation: | Yes, tumors for med in approximately 20% of nude mice inoculated with MSTO-211H cells |
| Comments: | The patient had not received prior radiation or chemotherapy. MSTO-211H cells have high affinity binding sites for EGF, and express Neuron specific enolase (NSE) and both the alpha and beta subunits of human chorionic gonadotropin (HCG). L-DOPA decarboxylase (DDC), bombesin and neurotensin were not detected.The cells overexpress the c-myc protooncogene, and no gene rearrangement or amplification was observed.They are positive for the expression of v-src, v-abl, v-erb B, c-raf 1, Ha-ras, Ki-ras, and N-ras.Expression of N-myc, L-myc, c-myb, c-fos, v-fes, v-fms and v-sis oncogene expression was not detected.The cells can reach a saturation density of 400000 cells per sq cm, but will slough off of the surface as they attain this density. For more information, please contact Cobioer (4008-750-250). |
