SNU-5（人胃癌细胞）
CBP60505
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| I. General information | |
| Synonyms: | SNU-5 |
| Background: | SNU-5 was line derived in 1987 by J. Park and associates from ascites of a patient with poorly differentiated carcinoma of the stomach. The patient had previously received chemotherapy including 5-fluorouracil, doxorubicin and mitomycin-C. Derived from metastatic site, ascites |
| Species: | Homo sapiens, human |
| Tissue: | stomach; derived from metastatic site: ascites |
| Disease: | gastric carcinoma |
| Gender: | Asian,female, 33 years |
| Morphology: | epithelial |
| Growth Mode: | suspension, multicell aggregates |
| Doubling Time: | 34 hrs |
| DNA Profile: | Amelogenin: X CSF1PO: 12 D13S317: 8,9 D16S539: 13 D5S818: 10 D7S820: 8,12 THO1: 9 TPOX: 11 vWA: 15,16 Cobioer’s Cell Line Authentication Service |
| Culture Medium: |
IMDM+20%FBS SNU-5完全培养基，# CBP60505M |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Antigen Expression: | Blood Type O; Rh + 。The cells express the surface glycoproteins carcinoembryonic antigen (CEA) and TAG 72. |
| Receptor Expression: | acetylcholine, muscarinic, expressed， vasoactive intestinal peptide (VIP), expressed， vasoactive intestinal peptide (VIP); acetylcholine, muscarinic |
| Oncogene: | myc +; erb B2 + |
| Tumor Formation: | Yes, the cells have a reported colony forming efficiency of 27% in semisolid medium. |
| Comments: | SNU-5 cells were positive for VIP receptors but lacked gastrin receptors. The cells express the surface glycoproteins carcinoembryonic antigen (CEA) and TAG-72. The cells are L-dopa decarboxylase (DDC) positive. For more information, please contact Cobioer (4008-750-250). |
