DU145（人前列腺癌肿瘤细胞）
CBP60345
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| I. General information | |
| Synonyms: | DU145 |
| Species: | Homo sapiens, human |
| Tissue: | prostate; derived from metastatic site: brain |
| Disease: | carcinoma |
| Gender: | male, 69 years, Caucasian |
| Morphology: | epithelial |
| Growth Mode: | adherent |
| DNA Profile: | D7S820: 7, 10, 11 D13S317: 12, 13, 14 D5S818: 10, 13 vWA: 17, 18, 19 THO1: 7 CSF1PO: 10, 11 TPOX: 11 D16S539: 11, 13 Amelogenin: X, Y Cobioer’s Cell Line Authentication Service |
| Culture Medium: |
RPMI-1640+10%FBS DU145完全培养基，#CBP60345M |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Antigen Expression: | Antigen expression: Blood Type O; Rh+ |
| Tumor Formation: | Yes, in nude mice; forms adenocarcinoma (grade II) consistent with prostatic primary |
| Comments: | The line is not detectably hormone sensitive, is only weakly positive for acid phosphatase and isolated cells form colonies in soft agar. The cells do not express prostate antigen. Ultrastructural analyses of both the cell line and original tumor revealed microvilli, tonofilaments, desmosomes, any mitochondria, well developed Golgi and heterogenous lysosomes. For more information, please contact Cobioer (4008-750-250). |
