TPOR(Ligand Dependent)/BaF3
CBP73266
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| I. Introduction | |
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Cell Line Name： |
TPOR(Ligand Dependent)/BaF3 |
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Host Cell: |
Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Complete Culture Medium: | RPMI-1640+10%FBS+2ug/ml puromycin+500nM Eltrombopag |
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Mycoplasma Status: |
Negative |
| II. Background | |
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Thrombopoietin receptor (TPOR) is a cytokine receptor protein present on the cell surface. The activation of TPOR by thrombopoietin (TPO) (a glycoprotein hormone) triggers an intracellular cascade of megakaryocytopoiesis for the formation of platelets. |
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| III. Representative Data | |
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1. WB of TPOR(Ligand Dependent)/BaF3
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2.Anti-proliferation assay
Figure 2. CTG Proliferation Assay of BaF3 TPOR Cells (C3), the EC50=34.1nM. |
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