CSF3R Q741*/BaF3
CBP73254
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| I. Introduction | |
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Cell Line Name： |
CSF3R Q741*/BaF3 |
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Host Cell: |
Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
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Application: |
Anti-proliferation assay and PD assay |
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Freeze Medium: |
90% FBS+10% DMSO |
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Complete Culture Medium: |
RPMI-1640+10%FBS |
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Mycoplasma Status: |
Negative |
| II. Background | |
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CSF3R, colony stimulating factor 3 receptor, encodes a cytokine receptor regulating proliferation and differentiation of myeloid progenitor cells (PMID: 27789332). CSF3R mutations commonly occur in chronic neutrophilic leukemia and acute myeloid leukemia (PMID: 23896413, PMID: 30348809). |
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| III. Representative Data | |
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1.WB of CSF3R Q741/BaF3
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2. Anti-proliferation assay
Figure 2. Anti-proliferation assay of three reference compounds on the CSF3R Q741/BaF3. |
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