IL22 Effector Reporter Cell
CBP74175
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| I. Background | |
| Interleukin-22 (IL-22) is protein that in humans is encoded by the IL22 gene.IL-22 primarily targets non-hematopoietic epithelial and stromal cells where it can promote proliferation and play a role in tissue regeneration. In addition, IL-22 regulates host defense at barrier surfaces. However, IL-22 has also been linked to several conditions involving inflammatory tissue pathology. | |
| II.Introduction | |
| Expressed gene: | IL22R |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Synonym(s): | Interleukin-22、IL-TIF、ILTIF、ZCYTO18 |
| Freeze Medium: | 90% FBS+10%DMSO |
| Culture Medium: | DMEM+10%FBS+2ug/ml puromycin+200ug/ml hrgromycin+5ug/ml blasticidin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Functional(Report Gene) Assay |
| III. Representative Data | |
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Figure 1. Recombinant IL22 Effector Reporter Cell constitutively expressing IL22R. |
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Figure 2. Recombinant IL22 Effector Reporter Cell constitutively expressing IL10RB. |
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Figure 3.Dose Response of Recombinant Human IL-22 in Human IL-22 Effector Reporter Cells(C8). |
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Figure 4.Inhibition of IL-22-induced Reporter Activity By IL-22 Neutralization Ab in IL-22 Effector Reporter Cells(C8). |
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