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OSMR Effector Reporter Cell

CBP74157

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I. Background
OSMR (Oncostatin M Receptor) is a Protein Coding gene. Diseases associated with OSMR include Amyloidosis, Primary Localized Cutaneous, 1 and Primary Cutaneous Amyloidosis. Among its related pathways are Interleukin-6 family signaling and Cytokine Signaling in Immune system. 
 
II.Introduction
Expressed gene: OSMR
Stability: 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Synonym(s): OSMRB, PLCA1, ...
Freeze Medium: 90% FBS+10%DMSO
Culture Medium: DMEM+10%FBS+200ug/ml hygromycin+2ug/ml puromycin+5ug/ml blasticidin
Mycoplasma Testing: Negative
Storage: Liquid nitrogen
Application(s): Functional(Report Gene) Assay
 
III. Representative Data

Figure 1. OSMR Effector Reporter Cell flow cytometry data.

 

Figure 2.Dose Response of Recombinant Human OSM in OSMR Effector Reporter Cells (C4).

 

Figure 3.Inhibition of hOSM-induced Reporter Activity by OSMR Blocking Ab in OSM Effector Reporter Cells (Clone4).

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