MDM2 T309G (rs2279744-T/T) Reference Standard
CBP10629
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| Introduction | |
| Format | Genomic DNA |
| Description | MDM2, MDM2 proto-oncogene, is an E3 ubiquitin protein ligase that mediates Tp53 degradation and therefore, regulates apoptosis and cell-cycle. Amplification and/or overexpression of MDM2 has been identified in several cancer types and amplification is common in liposarcoma and has been observed with Mdm2 overexpression in anaplastic lymphoma kinase (ALK)-negative inflammatory myofibroblastic tumors. |
| Technical Data | |
| DNA Change: | c.-5+309T>T |
| AA Change | T309T |
| Zygosity | Wild Type |
| Allelic Frequency | 0% |
| Transcript | ENST00000258149.5 |
| Cosmic ID | N/A |
| Chr position(GRCh37) | chr12-69202580-T-G |
| Buffer: | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purity | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |  |
| Storage | 4°C |
| Expiry | 36 months from the date of manufacture |
