FGFR2 p.S252W Reference Standard
CBP10110
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| Introduction | |
| Format | Genomic DNA |
| Description | FGFR2 S252W lies within the extracellular domain of the Fgfr2 protein (UniProt.org). S252W results in loss of ligand specificity, increased Fgfr2 activation, and is transforming in cell culture (PMID: 11121055, PMID: 18552176). |
| Technical Data | |
| DNA Change: | c.755C>G |
| AA Change | p.S252W |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 90.00% |
| Transcript | ENST00000358487 |
| Cosmic ID | COSM36903 |
| Chr position(GRCh37) | chr10:123279677 |
| Buffer: | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purity | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |  |
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
