ERBB2 p.R678Q Reference Standard
CBP10272
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| Introduction | |
| Format | Genomic DNA |
| Description | ERBB2 (HER2) R678Q lies within the Kpnb1 and Eea1-interacting region of the Erbb2 (Her2) protein (UniProt.org). R678Q demonstrates phosphorylation levels and transformation potential comparable to wild-type Erbb2 (Her2) protein in cell culture (PMID: 29533785) and xenograft models (PMID: 23220880). |
| Technical Data | |
| DNA Change | c.2033G>A |
| AA Change | p.R678Q |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 33.33% |
| Transcript | ENST00000269571 |
| Cosmic ID | COSM436498 |
| Chr position(GRCh37) | chr17:37879658 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing | Download for COA |
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
